John Libbey Eurotext

European Journal of Dermatology

Rosai-Dorfman disease and uveitis Article à paraître

Auteurs
1 Division of Dermatology,
Tohoku Medical and Pharmaceutical University,
1-12-1 Fukumuro,
Miyagino-ku,
Sendai 983-8512,
Japan
2 Division of Dermatology,
Department of Internal Related,
Kobe University Graduate School of Medicine,
7-5-1 Kusunoki-cho,
Chuo-ku,
Kobe 650-0017,
Japan
3 Department of Dermatology,
Nishiwaki Municipal Hospital,
652-1 Shimotoda,
Nishiwaki 677-0043,
Japan
4 Department of Infection and Host Defense,
Graduate School of Medicine,
Chiba University,
1-8-1 Inohara,
Chuo-ku,
Chiba 260-8670,
Japan

Rosai-Dorfman disease (RDD), also known as sinus histiocytosis with massive lymphadenopathy, is a rare benign disease characterized by persistent massive lymphadenopathy caused by increased numbers of macrophages within lymph node sinuses [1, 2]. These cells are often large and exhibit abnormal behaviour, engulfing intact cells (such as lymphocytes, erythrocytes, and plasma cells) into the cytoplasm, a phenomenon known as “emperipolesis”. Although the classic clinical presentation is painless [...]