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European Journal of Dermatology

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Residents’ corner September 2011. CarpeDIEM – Birbeck granule in Langerhans cell histiocytosis Volume 21, numéro 5, September-October 2011

Auteurs
Department of Dermatology, University of Tuebingen, Liebermeisterstrasse 25, 72076 Tübingen, Germany

ejd.2011.1540 Auteur(s) : Emmanuella Guenova emmanuella.guenova@gmail.com, Martin Schaller Department of Dermatology, University of Tuebingen, Liebermeisterstrasse 25, 72076 Tübingen, Germany Langerhans cell histiocytosis (LCH) is characterized by lesions rich in langerin+ (CD207+)/CD1a+/Birbeck granule+ cells, with a dendritic Langerhans cell (LC) phenotype. The clinical course of the disease may range broadly, from spontaneous remission sometimes to a fatal outcome. Histology and immunocytochemical [...]