John Libbey Eurotext

European Journal of Dermatology


Pustulosis palmaris et plantaris successfully treated with leukotriene antagonist Volume 24, numéro 6, November-December 2014


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1 Department of Environmental Immuno-Dermatology,
2 Department of Dermatology,
Yokohama City University Medical Center,
3-9 Fukuura, Kanazawa-ku,
Yokohama 236-0004, Japan

Pustulosis palmaris et plantaris (PPP) is a chronic and relapsing inflammatory disease, characterized by multiple pustules and erythematous plaques on the palms and solesof the feet [1]. Pathologically, PPP pustules aresubcorneal blisters, containing polymorphonuclear leukocyte infiltrations. However, the pathogenetic mechanisms of PPP are unclear, although it is well-known that metal allergens, smoking and focal infections such as tonsillitis or tooth infection are exacerbating factors. PPP is treated [...]