John Libbey Eurotext

European Journal of Dermatology

Plexiform fibrohistiocytic tumor Volume 14, issue 2, March-April 2004

Résumé : We report the case of a 6‐year‐old Japanese boy with a plexiform fibrohistiocytic tumor on the right perioral region. Clinically, the tumor, 5 mm in diameter, was a solitary, hard, erythematous, slowly growing, painless nodule. There was no preceding trauma. Histology revealed a well‐circumscribed plexiform lesion with a biphasic appearance. Immunohistochemistry demonstrated CD68 positivity in many of mononuclear macrophages. The lesion was negative for S‐100 protein, lysozyme, CD57 and factor XIIIa. Interestingly, the tumor showed an intradermal location from superficial to deep dermis, and lacked osteoclast‐like giant cells. During the follow‐up for 9 months after the resection, there was no recurrence or metastasis.

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