John Libbey Eurotext

European Journal of Dermatology


Persistent neutrophilic scarring alopecia triggered by anti-TNF blockade for Crohn's disease Volume 28, numéro 3, May-June 2018


  • Figure 1
Department of Dermatology, Venereology and Allergology, University Medical Center, Göttingen, Germany

A 36-year-old woman with Crohn's disease presented with skin eruptions that had developed during treatment with infliximab. Due to therapeutic failure with azathioprine alone, infliximab (5 mg/kg every eight weeks) had been added in June 2008. After the third infliximab infusion, she developed multiple palmoplantar pustules, typical for TNF antagonist-induced paradoxical pustulosis palmoplantaris. The patient, a smoker, did not have any personal or familial history of psoriasis. The cutaneous palmoplantar [...]