John Libbey Eurotext

European Journal of Dermatology


Oral tacrolimus for the treatment of generalized morphea Volume 26, numéro 1, January-February 2016


  • Figure 1
1 Department of Dermatology,
Japan Community Healthcare
Organization Osaka Hospital
2 Department of Dermatology,
Tokyo Medical and Dental University,
Graduate School of Medicine,
Yushima 1-5-45, Bunkyo-ku,
Tokyo 113-8519, Japan
3 Department of Respiratory Medicine,
Allergy, and Rheumatic Diseases,
Osaka University Graduate School of Medicine

A 27-year-old Japanese woman presented with erythema on the trunk and extremities and a 10-day history of low-grade fever (approximately 37.5 °C) in February 2014. At the age of seven, the patient had been diagnosed with morphea based on the histopathological findings of a skin biopsy taken from an erythematous lesion of the right leg. The erythema gradually spread from the limbs to the trunk and whitish atrophic plaques also appeared. 15 years previously, she had been diagnosed with an autoimmune [...]