JLE

European Journal of Dermatology

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Oculomucosal and gastrointestinal involvement in Epstein-Barr virus-associated hydroa vacciniforme Volume 22, numéro 3, May-June 2012

Auteurs
Department of Dermatology, Okayama Graduate School of Medicine, 2-5-1 Shikata-cho Kita-Ku, 700-8558 Okayama, Japan

In a series of patients with Epstein-Barr virus (EBV)-associated hydroa vacciniforme (HV) and related disorders, we reviewed the incidence of oculomucosal and gastrointestinal involvement. Of 63 patients with EBV-related HV and/or hypersensitivity to mosquito bites (HMB), 11 patients (17.5%) presented with mucosal lesions such as aphthous stomatitis and ulcerative gingivitis, 3 patients (4.8%) had ocular symptoms including iritis, conjunctival hyperemia and corneal erosions, and 2 patients (3.2%) presented with severe HV complicated gastrointestinal involvement. Oculomucosal lesions are sometimes complicated in patients with EBV-related HV and HMB, and gastrointestinal involvement may occur in the severe form.