John Libbey Eurotext

European Journal of Dermatology

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Narrow-band ultraviolet B phototherapy for early stage mycosis fungoides Volume 18, numéro 6, Novembre-Décembre 2008

Auteurs
Department of Dermatology, No. 1 Hospital of China Medical University, 155 North Nanjing Street, Shenyang 110001, China
  • Mots-clés : mycosis fungoides, narrow-band ultraviolet B, phototherapy
  • DOI : 10.1684/ejd.2008.0515
  • Page(s) : 660-2
  • Année de parution : 2008

Recently there have been some reports concerned the treatment of early stage mycosis fungoides (MF) with narrow-band ultraviolet B (NB-UVB) phototherapy. In most of the previous reports, NB-UVB phototherapy was given three times a week on non-consecutive days. Our aim was to evaluate the effect of a twice weekly regimen of NB-UVB phototherapy in the treatment of early-stage MF. Eight patients with early stage MF received NB-UVB phototherapy twice weekly. Six patients (75%) had a complete response in a mean of 23.4 treatments, two (25%) had a partial response. Upon discontinuation of treatment, four patients with complete response relapsed in a mean time to relapse of 5 months. The twice weekly regimen of NB-UVB phototherapy is effective and well-tolerated in the treatment of early stage MF.