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European Journal of Dermatology

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Multiple neurological abnormalities, including pontine hemorrhage, multiple sclerosis and aseptic meningitis, during anti-TNF-α therapy in psoriatic arthritis Volume 25, numéro 5, September-October 2015

Illustrations


  • Figure 1
Auteurs
1 Department of Dermatology,
2 Department of Neurology,
Kyoto University Graduate School of Medicine,
54 Shogoin-Kawara, Sakyo,
Kyoto 606-8507, Japan

Psoriatic arthritis (PsA) is an inflammatory arthritis that affects 5-30% of patients with cutaneous psoriasis [1]. Since tumor necrosis factor (TNF)-α plays critical roles in the development of erosive joint damage, TNF-α inhibitors are an effective treatment for PsA [2]. TNF-α inhibitors are generally considered to be safe with rare severe side effects, but have been reported to cause various immune-mediated diseases, including demyelinating diseases [3]. Recently, we experienced a case of PsA [...]