European Journal of Dermatology
MENULinear IgA/IgG bullous dermatosis reacts with multiple laminins and integrins Volume 25, numéro 5, September-October 2015
Auteurs
1 Department of Dermatology, Kurume University School of Medicine, and Kurume University Institute of Cutaneous Cell Biology, 67 Asahimachi, Kurume, Fukuoka 830-0011, Japan
2 Department of Dermatology, Faculty of Medicine, University of Yamanashi, Chuo, Yamanashi, Japan
3 Department of Dermatology, Osaka City University Graduate School of Medicine, Osaka, Japan
4 Division of Biological Science, Graduate School of Science, Nagoya University, Nagoya, Aichi, Japan
* Reprints
a These three authors contributed equally to this study.
- Mots-clés : linear IgA/IgG bullous dermatosis, integrin α6β4, laminin-332, laminin-γ1
- DOI : 10.1684/ejd.2015.2555
- Page(s) : 418-23
- Année de parution : 2015
In the progress of biochemical and molecular biological studies, most constituent proteins in the epidermal basement membrane zone (BMZ) have been identified as autoantigens for various subepidermal autoimmune bullous diseases [1]. These autoantigens include BP230 and BP180 in BP [2, 3], BP180 in pemphigoid gestationis and anti-BP180-type mucous membrane pemphigoid (MMP) [4], type VII collagen in epidermolysis bullosa acquisita (EBA) [5], the 120 kDa LAD-1, a truncated ecto-domain of BP180 in linear [...]