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European Journal of Dermatology

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Idiopathic myelofibrosis and pyoderma gangrenosum involving a mutation of Janus kinase 2 ( JAK2V617F), showing poor prognosis Volume 23, numéro 2, March-April 2013

Auteurs
Department of Dermatology,, Department of Pathology,, Department of Internal Medicine, Kitasato University School of Medicine, Sagamihara, Kanagawa, 228-8555, Japan

ejd.2013.1956 Auteur(s) : Maejima Hideki1 hm4765@yahoo.co.jp, Takano Tetsurou1, Funatsu Sakae1, Katsuoka Kensei1, Oobe Makoto2, Kamata Toshinobu3 1 Department of Dermatology, 2 Department of Pathology, 3 Department of Internal Medicine, Kitasato University School of Medicine, Sagamihara, Kanagawa, 228-8555, Japan Janus kinase (JAK)-signal transducers and activators of transcription (STAT) signalling are activated by a wide array of cytokines, including colony-stimulating factors. The JAK-STAT pathway [...]