John Libbey Eurotext

European Journal of Dermatology

Expression of keratin 1, keratin 10, desmoglein 1 and desmocollin 1 in the epidermis: possible downregulation by interleukin-4 and interleukin-13 in atopic dermatitis Volume 27, numéro 3, May-June 2017

Illustrations

  • Figure 1
  • Figure 2
  • Figure 3

Tableaux

Auteurs
1 Department of Dermatology, Tokyo Women's Medical University, Tokyo, Japan
2 Department of Microbiology and Immunology, Tokyo Women's Medical University, Tokyo, Japan
* Reprints
  • Mots-clés : adhesion molecule, atopic dermatitis, interleukin-4, interleukin-13, stratum spinosum, structural protein
  • DOI : 10.1684/ejd.2017.2985
  • Page(s) : 247-53
  • Année de parution : 2017

Background

In the pathogenesis of atopic dermatitis (AD), skin barrier dysfunction and T-helper (Th) type 2 immune reactions play important roles. Alterations in the stratum spinosum of AD have not been studied in much detail.