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European Journal of Dermatology

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Contact sensitizers decrease 33D1 expression on mature Langerhans cells Volume 9, numéro 3, April- May 1999

Auteurs
L’Oréal Advanced Research, Life Sciences Research, 1, avenue Eugène-Schueller, BP 22, 93601 Aulnay-sous-Bois Cedex, France.
  • Page(s) : 185-90
  • Année de parution : 1999

Allergic contact hypersensitivity (CHS) is a T cell-mediated immune response to highly reactive low-molecular-weight chemicals that penetrate the skin. As opposed to irritant contact dermatitis, a non specific cutaneous inflammation, CHS, develops in two phases: initial exposure to an allergen induces the clinically silent immune response necessary for sensitization (induction phase) [1], and re-exposure to the allergen results in clinical [...]