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Tumor necrosis factor-alpha and its soluble receptors in plasma and cerebrospinal fluid of multiple sclerosis patients treated with methylprednisolone. Volume 10, numéro 3, September 1999

Auteurs
Neurological Institute “C. Mondino Foundation”, via Palestro 3, I-27100 Pavia, Italy
  • Page(s) : 431-6
  • Année de parution : 1999

INTRODUCTION Multiple sclerosis (MS), a multifocal inflammatory disease of the central nervous system (CNS), is characterised by myelin destruction and selective oligodendrocyte damage [1]. This process could be the result of an immune response to CNS self-antigens. Although the initial pathogenic events that lead to MS remain obscure, the final events, which are involved in the formation of demyelinating plaques, have been [...]