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Regulation of interleukin-18 (IL-18) expression in keratinocytes (HaCaT): implications for early wound healing Volume 11, numéro 4, December 2000

Auteurs
Institut für Allgemeine Pharmakologie und Toxikologie, Klinikum der JWG-Universität Frankfurt/M, Theodor-Stern-Kai 7, D-60590 Frankfurt/M., Germany.
  • Page(s) : 626-33
  • Année de parution : 2000

INTRODUCTION After injury, tissue regeneration is characterized by overlapping phases that involve hemostasis, inflammation, cell proliferation, and the remodeling phase of repair. These processes encompass macrophage accumulation, fibroblast ingrowth, matrix deposition, and angiogenesis into the wound site [1, 2]. The inflammatory phase is central to healing, as infiltrating immune cells initiate and trigger repair by secretion of growth [...]