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Receptor-like properties of the 26 kDa transmembrane form of TNF Volume 12, numéro 3, September 2001

Auteurs
Institute of Biochemistry, Biological Research Center of the Hungarian Academy of Sciences, H-6701 Szeged, P.O. Box 521, Hungary
  • Page(s) : 411-9
  • Année de parution : 2001

ABBREVIATIONS ICD: intracellular domain IL-1: interleukin-1 beta NLS: nuclear localization signal PE: phycoerythrine TNF: tumor necrosis factor alpha INTRODUCTION Tumor necrosis factor alpha (TNF) is described as a soluble, anti-tumor, pro-inflammatory cytokine, and a key modulator of the activity of the immune system [1, 2]. Depending on the type and developmental stage of target cells, [...]