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European Cytokine Network

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Prolactin activates interferon regulatory factor-1 expression in normal lympho-hemopoietic cells Volume 11, numéro 3, September 2000

Auteurs
Department of Pharmacology, Medical School, Free University of Brussels (VUB), Laarbeeklaan, 103, B-1090 Brussels, Belgium
  • Page(s) : 435-42
  • Année de parution : 2000

INTRODUCTION PRL is synthesized and secreted primarily by the anterior pituitary. Its best known functions in mammals include stimulation of growth and differentiation of the mammary gland, the ovary and male accessory sex organs [1]. PRL is also expressed in extra-pituitary tissues [2, 3] and has been shown to affect immune responses [2, 3]. PRL-receptor (PRL-R), a member of the hemopoietin/cytokine receptor superfamily [4, 5], is expressed [...]