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European Cytokine Network

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Obesity and inflammation Volume 29, numéro 3, September 2018

Illustrations

  • Figure 1
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Auteurs
1 Department of Environmental Medicine/Department of Gastroenterology, Human Nutrition and Internal Medicine, Poznan University of Medical Sciences, Fredry 10, Poznan 61-701, Poland
2 Department of Gastroenterology, Human Nutrition and Internal Medicine, Poznan University of Medical Sciences, Fredry 10, Poznan 61-701, Poland
3 AI Centrum Medyczne, Swietojanska 1, Poznan61-113, Poland
4 Department of Hypertensiology, Angiology and Internal Medicine, Poznan University of Medical Sciences, Fredry 10, Poznan 61-701, Poland
* Correspondence: Jacek Karczewski, Department of Environmental Medicine/Department of Gastroenterology, Human Nutrition and Internal Medicine, Poznan University of Medical Sciences, Fredry 10, Poznan 61-701, Poland
  • Mots-clés : obesity, inflammation, adipose tissue, insulin resistance
  • DOI : 10.1684/ecn.2018.0415
  • Page(s) : 83-94
  • Année de parution : 2018

The prevalence of obesity has recently increased dramatically and has contributed to the increasing prevalence of various pathological conditions, including type 2 diabetes mellitus, nonalcoholic fatty liver disease, asthma, various types of cancer, cardiovascular and neurodegenerative diseases, and others. Accumulating evidence points to localized inflammation in adipose tissue, which, in turn, promotes systemic low-grade inflammation as a primary force contributing to the development of these pathologies. A better understanding of the underlying mechanisms behind obesity-induced adipose tissue inflammation is required to develop effective therapeutic or prophylactic strategies. This review is aimed to present the current knowledge of adipose tissue inflammation associated with obesity.