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Moderate inhibitory effect of interleukin-10 on human neutrophil and monocyte chemotaxis in vitro. Volume 9, numéro 3, September 1998

Auteurs
Immunology Laboratory and INSERM U. 479, X. Bichat University, Paris, France

INTRODUCTION Phagocytes clear invading organisms and inflammatory debris. Polymorphonuclear neutrophils (PMN) and monocytes are attracted to sites of inflammation or infection through the production of chemoattractant mediators. As a result of chemoattractant receptor activation, phagocytes are stimulated to adhere to the endothelium and move through the vessel wall into the tissues [1, 2]. There, they engulf microorganisms, [...]