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Localization of a receptor nonapeptide with a possible role in the binding of the type I interferons Volume 11, numéro 4, December 2000

Auteurs
Laboratory of Viral Oncology, CNRS-UPR 9045, 7, rue Guy-Moquet, 94801 Villejuif, France.
  • Page(s) : 560-73
  • Année de parution : 2000

INTRODUCTION Human interferons (IFNs) are a family of cytokines composed of four distinct species: alpha, beta, gamma and oméga based on nucleotide and amino acid sequence homology. The type I IFNs, alpha, beta, and oméga, are encoded by at least 12 functional IFN-alpha genes, a related IFN-oméga gene, and one, more distantly related, IFN-beta gene. Type II IFN, or IFN-gamma, is encoded by an unrelated gene and binds [...]