European Cytokine Network
MENULeukemia inhibitory factor involvement in human ulcerative colitis and its potential role in malignant course. Volume 9, numéro 4, December 1998
Illustrations
R. Guimbaud, V. Abitbol, V. Bertrand, G. Quartier, L. Chauvelot-Moachon, J.-P. Giroud, D. Couturier and S. Chaussade
Service d’Hépatogastroentérologie, Hôpital Cochin, 27, rue du Faubourg-Saint-Jacques, 75014 Paris, France. Tel: (+33) 1.42.34.15.38, Fax: (+33) 1.42.34.50.09, e-mail: stanislas.chaussade@cch.ap-hop-paris.fr
- Page(s) : 607-12
- Année de parution : 1999
INTRODUCTION LIF, a member of the hematopoietic family of growth factors, is a pleitropic cytokine initially identified by its growth-promoting activity on the murine IL-3-dependent DA-1 cell line [1]. Since, several other activities have been ascribed to LIF, mainly: proinflammatory actions, tumorogenesis and embryonic development. LIF has been detected in normal as well as in tumor cells. In normal adult mouse many tissues [...]