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European Cytokine Network

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Interleukin-13 and IgE production in rat experimental schistosomiasis. Volume 11, numéro 2, June 2000

Auteurs
Institut Pasteur de Lille, INSERM U. 167, 1, rue du Pr. Calmette, BP 245, 59019 Lille Cedex, France.
  • Page(s) : 241-50
  • Année de parution : 2000

INTRODUCTION IL-4 and IL-13 are considered to be key cytokines in the induction and maintenance of IgE production [1, 2]. IL-13 is produced by several cell types, such as activated T cells, dendritic cells, mast cells and alveolar macrophages [3, 4]. In contrast to IL-4, IL-13 does not act on T cells, due to the lack of expression of functional IL-13 receptors by this cell population [5, 6]. These two cytokines have many similar biological [...]