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European Cytokine Network

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Induction of interleukin-2 receptor alpha (IL-2Ralpha) expression by interleukin-2: important role of the interleukin-2 receptorv beta chain region between the two Stat5 docking sites Volume 13, numéro 3, September 2002

Auteurs
U526 INSERM, Faculté de Médecine-Pasteur, 06107 Nice Cedex 02.
  • Page(s) : 331-9
  • Année de parution : 2002

INTRODUCTION Interleukin-2 (IL-2) influences several components of the immune system, including T and B cells, natural killer cells and monocytes. Three classes of IL-2 receptors are known: low affinity receptors containing only the alpha chain, intermediate affinity receptors consisting of beta and gamma chains, and high affinity receptors that contain all three chains (for review [1]). In T lymphocytes, IL-2Rbeta and gammac are [...]