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European Cytokine Network

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Effect of proinflammatory cytokines on interleukin-8 mRNA expression and protein production by isolated human alveolar epithelial cells type II in primary culture Volume 11, numéro 4, December 2000

Auteurs
Research Centre Borstel, Medical Hospital, Parkallee 35, 23845 Borstel, FRG.
  • Page(s) : 618-25
  • Année de parution : 2000

INTRODUCTION During the last decade, increasing evidence has been provided to support the idea that the human CXC chemokine interleukin (IL)-8 is involved in acute and chronic inflammatory lung diseases [1], which are characterized by recruitment of neutrophils into the bronchoalveolar space and lung tissue, such as adult respiratory distress syndrome [2], idiopathic pulmonary fibrosis [3, 4] and cystic fibrosis [5]. It is generally thought [...]