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European Cytokine Network

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Cytokine and molecular networks in sepsis cases: a network biology approach Volume 29, numéro 3, September 2018

Illustrations

  • Figure 1
  • Figure 2

Tableaux

Auteurs
1 Department of Laboratory Medicine, Incheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea
2 Department of Thoracic and Cardiovascular Surgery, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea
3 Department of Laboratory Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea
4 Laboratory for Development and Evaluation Center, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea
* Corresponding author: Y. Kim, Department of Laboratory Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, 222 Banpo-daero, Seocho-gu, Seoul 06591, Republic of Korea
a Authors equally contributed to this work.
  • Mots-clés : sepsis, cytokine molecules, network analysis, network topology, GEO dataset
  • DOI : 10.1684/ecn.2018.0414
  • Page(s) : 103-11
  • Année de parution : 2018

Background

Sepsis is a life-threatening condition of organ dysfunction caused by a dysregulated host immune response to infection. We performed network analysis of cytokine molecules and compared network structures between a systematic inflammatory response syndrome (SIRS) or normal control (NC) group and a sepsis group.