Auteur(s) : Atsushi Miyamoto, Hiroshi Moriki, Shigeru Ishiguro, Akira Nishio , Department of Veterinary Pharmacology, Faculty of Agriculture, Kagoshima University, Kagoshima, Japan.
Illustrations
Figure 1 NO production from the thoracic aorta
during 6 h incubation in vitro with and without endotoxin
(lipopolysaccharide: LPS).: control rats; : Mg-deficient rats (n =
5 in each group).*p < 0.05 compared with corresponding LPS
minus.**p < 0.05 compared with corresponding control rat.
Figure 2 Effect of endothelium-denudation on NO
production from thoracic aortas of Mg-deficient rats (n = 5).
Figure 3 Effect of a selective iNOS inhibitor
(1400W) on NO production from thoracic aortas of control and
Mg-deficient rats.: control rats; : Mg-deficient rats (n = 6 in
each group).*p < 0.05 compared with corresponding control
rat.
Figure 4 Effect of antibodies to IgG2a,
TLR4 and CD14 on endotoxin (lipopolysaccharide: LPS)
(1 μg/mL)-induced NO production from thoracic aortas of
control () and Mg-deficient () rats (n = 4 in each group).*p <
0.05 compared with corresponding control rat.**p < 0.05 compared
with corresponding anti-IgG2a.
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