Auteur(s) : Jolanta Myśliwska, Joanna Więckiewicz, Łukasz Hak, Janusz Siebert, Jan Rogowski, Krzysztof Szyndler, Andrzej Myśliwski , Department of Immunology, Medical University of Gdańsk, Ul. Dębinki 1, 80-210 Gdańsk, Poland Tel.: (+00 48) 58 349 14 33; fax: (+00 48) 58 349 14 33, Department of Family Medicine, Medical University of Gdańsk, Poland, Academic Clinic of Cardiosurgery, Medical University of Gdańsk, Poland, Department of Histology, Medical University of Gdańsk, Poland.
Illustrations
Figure 1 Effect of IL6 genotype on spontaneous IL6
secretion.WBCC cultures were set up for the following number of
patients: GG n = 70; CC n = 55; GC n = 120. The differences
between genotypes in IL6 secretion after 4 h (p = 0.04),
24 h (p = 0.03) and 48 h (p = 0.04) were statistically
significant (Kruskal-Wallis ANOVA).The values represent arithmetic
means ± S.D.
Figure 2 IL6 serum concentration.IL6 serum level was
measured in all patients. Forty six patients were affected with
one-vessel disease, 130 with two-vessel disease and 144 with
three-vessel disease. The differences between IL6 concentrations
were statistically significant (ANOVA; p = 0.0001).The values
represent arithmetic means ± S.D.
Figure 3 Spontaneous secretion of IL6.WBCC cultures
were incubated without stimulants and IL6 measured in supernatants.
There were statistically significant differences between IL6
concentrations in cultures of patients with differing numbers of
affected coronary arteries at 24 h (p = 0.03) and 48 h (p
= 0.03) (Kruskal-Wallis ANOVA). The values represent arithmetic
means ± S.D.
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