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European Cytokine Network

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IFN-beta stimulates the production of beta-chemokines in human peripheral blood monocytes. Importance of macrophage differentiation Volume 12, numéro 4, December 2001

Auteurs
Laboratory of Virology, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Rome, Italy.
  • Page(s) : 597-603
  • Année de parution : 2002

INTRODUCTION Monocytes and macrophages are involved differently in a variety of immunoregulatory, phagocytic and secretory functions. During maintenance of immune homeostasis, monocytes circulate and transmigrate through vascular endothelium and localize in peripheral tissues [1, 2]. Human peripheral blood monocytes mature into different types of tissue histiocytes when they migrate from the bloodstream to various tissues. This differentiation [...]