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European Cytokine Network

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Interferon-alpha suppresses leptin levels: studies in interferon-alpha treated patients with hepatitis C virus infection and murine adipocytes Volume 13, numéro 2, June 2002

Auteurs
Department of Medicine, University of Innsbruck, Anichstraße 35, 6020 Innsbruck.
  • Page(s) : 225-9
  • Année de parution : 2002

INTRODUCTION Hepatitis C virus infection is a major cause of chronic liver disease [1-3]. The clinical course seldom involves acute hepatitis, but commonly proceeds directly to chronic hepatitis, with the potential sequelae of cirrhosis and hepatocellular carcinoma. Interferon alpha (IFN-alpha) has proven clinical success in the treatment of hepatitis C virus infection [4, 5]. Currently, the detailed molecular mechanisms of action of IFN-alpha [...]