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European Cytokine Network

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Undetectable levels of tumor necrosis factor-alpha, nitric oxide and inadequate expression of inducible nitric oxide synthase in congenital hypothyroidism Volume 14, numéro 1, March 2003

Auteurs
Hospital General Universitario Gregorio Marañón, Servicio de Inmunología, C/Dr. Esquerdo 46, 28007 Madrid, Spain.
  • Page(s) : 65-8
  • Année de parution : 2003

INTRODUCTION Nitric oxide (NO) is a free-radical gas produced by many cell types, which has a broad repertoire of important pathophysiogical functions [1-3]. NO is synthesised from L-arginine by a family of three nitric oxide synthase (NOS) proteins: neuronal or NOS1, endothelial or NOS3, and inducible or NOS2 [4]. NO has a role as a neurotransmitter and regulator of blood pressure, it has vasodilator and antiplatelet, [...]