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LPS and Freund’s adjuvant initiate different inflammatory circuits in experimental autoimmune thyroiditis Volume 14, numéro 1, March 2003

Auteurs
Hôpital Européen Georges Pompidou, Service d'Anatomie et Cytologie Pathologiques, 20-40, rue Leblanc, 75015 Paris, France.
  • Page(s) : 52-9
  • Année de parution : 2003

Introduction The experimental induction of autoimmune diseases in rodents is critically dependent upon the administration, together with the autoantigen, of an appropriate adjuvant. The role of the adjuvant is still not totally understood [1]. Adjuvants are believed to facilitate the response of autoreactive T cell precursors which would otherwise ignore self-antigens or be unresponsive to them, by providing a set [...]