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Evidence for tumor necrosis factor receptors (TNFRs) in human MRC5 fibroblast cells. Volume 12, numéro 1, March 2001

Auteurs
Laboratoire Interactions Cellulaires Parasite-Hôte, EA.UJF 2940, CNRS-ER 2014, Faculté de Médecine et de Pharmacie de Grenoble, Université Joseph-Fourier, Grenoble-I, Domaine de la Merci, 38706 La Tronche Cedex, France.
  • Page(s) : 147-53
  • Année de parution : 2001

INTRODUCTION Tumor necrosis factor alpha (TNF-alpha), an inflammatory cytokine primarily produced by activated macrophages, exerts a wide range of both beneficial and detrimental biological effects. Among the beneficial effects is the critical role played by TNF-alpha in the host defence against micro-organisms, in particular against fungi (Candida albicans, Cryptococcus neoformans) [1], intracellular bacteria (Listeria monocytogenes, Mycobacterium [...]