John Libbey Eurotext



Human herpesvirus 6 and 7 infections in renal allografts Volume 5, issue 5, Septembre - Octobre 2001


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Laboratoire de virologie, Cervi, Upres EA 2387, Groupe hospitalier Pitié-Salpêtrière, 83, boulevard de l'Hôpital, 75013 Paris

HHV6 and HHV7 are increasingly recognized as significant opportunistic pathogens in organ transplant recipients. Active infections are frequent after kidney allograft, but the clinical consequences are rather unknown. Nevertheless, HHV6 seems to be significantly associated with graft rejection, and HHV7 appears to be a possible cofactor in the development of human cytomegalovirus disease in renal transplant patients. The interactions between the three members of the Betaherpesvirinae subfamily could lead to some pathologic clinical manifestations.