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 Printable version |
A new immunoassay for estradiol on the Advia-Centaur (Siemens) system: analytical and clinical performances |
Annales de Biologie Clinique. Volume 70, Number 5, 581-9, Septembre-Octobre 2012, Article original
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 Résumé
Article gratuit
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Author(s) : Mounia Lachgar, Guillaume Moulin, Joëlle Taieb |
Summary : The objective of this study is to present results for measurement of estradiol (E
2) in serum and control materials with a new automated assay (eE
2) that could be used in random continuous access mode on the Siemens laboratories Advia-Centaur immunoassay analyzer. We evaluated the imprecision (within and between run), the linearity, the limit of detection, and the functional sensitivity. We have tested the assay for monitoring ovulation stimulation for
in vitro fertilization and embryo transfer (IVF-ET) throughout the most frequent protocol utilized in our IVF centre (n \= 247). Results are compared to those obtained by the E
26 assay, one other assay on the Advia-Centaur immunoassay analyzer (Siemens), routinely used in our hormonology department. The obtained results show that the new assay presents better analytical performances (precision, linearity, limits of detection and sensibility) than the previous technique. |
Keywords : estradiol, Advia-Centaur, immunoassay |
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