Clinical and epidemiological survey of Buruli ulcers in young people in Bénin

Richard Josse; Lorenzo Andrès; Claude Zinsou; Sévérin Anagonou; Augustin Guedenon; Marie Botineau; Joseph Catraye; Joseph Foundohou; Jean-Étienne Touzé

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Clinical and epidemiological survey of Buruli ulcers in young people in Bénin

Cahiers d'études et de recherches francophones / Santé . Volume 2, Number 1, 23-7, Janvier-Février 1992, Étude originale

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Author(s) : Richard Josse, Lorenzo Andrès, Claude Zinsou, Sévérin Anagonou, Augustin Guedenon, Marie Botineau, Joseph Catraye, Joseph Foundohou, Jean-Étienne Touzé, Direction nationale de la protection sanitaire, service d’épidémiologie et de recherches opérationnelles, BP 883, Cotonou, République du Bénin, Hôpital « Terre des Hommes » à Sagon et Bohicon (Zou, Bénin), Laboratoire de référence des mycobactéries d’Akpakpa, Cotonou, Bénin, Service technique d’intervention d’Abomey (Zou, Bénin), Institut de médecine tropicale du Service de santé des armées. Le Pharo, Marseille, France..

Summary : The authors report the results of a clinical, bacteriological and therapeutic study of 74 Bénin children and teenagers with Mycobacterium ulcerans skin lesions. Most (77%) of the patients had stage 3 ulceration. Acid-fast bacilli were isolated from 37 of 45 patients tested. Medical treatment (antituberculosis and antileprosis drugs) is often disappointing, and mutilating surgery is often unavoidable. When necessary, excision and repeated skin grafting gives good results in 50-75% of patients.

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