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Executive dysfunction in preschool children with neurofibromatosis type 1 Volume 10, issue 3, Juillet-Août-Septembre 2018

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Authors
1 Centre référent des troubles d’apprentissage,
Immeuble Jean-Monnet,
CHU de Nantes,
44093 Nantes cedex 1,
France
2 Laboratoire de psychologie des Pays-de-la-Loire,
université d’Angers,
UBL, EA4638,
11, boulevard Lavoisier,
49045 Angers cedex 1,
France
3 Centre de compétence nantais de neurofibromatose,
CHU de Nantes,
44093 Nantes cedex 1,
France
4 Centre référent des troubles d’apprentissage,
CHU de Brest,
29200 Brest,
France
* Correspondance

This study aimed to examine executive function in preschool-age children with neurofibromatosis type 1 (NF1). Eighteen children with NF1 aged 3-6 years were matched to 37 healthy controls by age, gender and parental education. Both groups were administered three executive tasks (Sun-moon Stroop, Corsi blocks, preschool Brixton). To examine the relationship between executive function and intellectual ability, children with NF1 were administered WPPSI-III, whereas healthy controls underwent Cubes and Information subtests. Preschool-age children with NF1 performed significantly less well than healthy controls on many executive function tasks, independently from the slight intellectual level decline noted. The results highlight the importance of early executive function assessment in children with NF1.

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