John Libbey Eurotext

Médecine thérapeutique / Pédiatrie


Food protein-induced enterocolitis syndrome (FPIES), what you need to know Volume 20, issue 2, Avril-Mai-Juin 2017


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1 CHU-Lenval, Hôpitaux pédiatriques de Nice, Médecine pédiatrique, 57 avenue de la Californie, 06200 Nice
2 CHU-Lenval, Hôpitaux pédiatriques de Nice, Consultations d’allergologie pédiatrique, 57 avenue de la Californie, 06200 Nice
* Tirés à part
  • Key words: FPIES, digestive symptoms, infant
  • DOI : 10.1684/mtp.2017.0635
  • Page(s) : 88-95
  • Published in: 2017

Food protein induced enterocolitis syndrome (FPIES), is a non-IgE mediated food allergy (FA) which seems to expand, and occurring in infancy. It is mainly related to cow's milk and manifests as a chronic digestive disease when the food is daily ingested, or in its acute form with potentially life-threatening vomiting/diarrhea/dehydration, confusing with anaphylaxis. Solid foods have also been demonstrated, reminded of adult form, mainly due to shellfish. This disease is usually unknown by clinicians. Its diagnostic is based on clinical history, and differential diagnosis elimination. Acute management begins with clinical evaluation, then administer normal saline bolus quickly. Parenteral ondansetron can be used to stop vomiting. Nutritional management implicate elimination of the offending foods. Only the oral food challenge in hospital can be done to determine resolution of FPIES after a long time of no symptom.