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Health of children born after frozen-thawed embryo transfer Volume 21, issue 4, Octobre-Novembre-Décembre 2019

Tables

Authors
1 Service de biologie de la reproduction, Cecos, hôpital Tenon, AP-HP, Sorbonne université, Paris, France
2 Centre de recherche Saint-Antoine, Inserm, UMR S938, hôpital Saint-Antoine, Paris, France
3 Unité de biologie de la reproduction, Cecos, hôpital Antoine Béclère, AP-HP, université Paris Saclay, Clamart, France
4 Assistance médicale à la procréation, Cecos, CHU Estaing, Clermont Ferrand, France
5 Imagerie moléculaire et stratégie théranostique (ImoST), Inserm 1240, Equipe 2, Clermont-Ferrand, France
* Tirés à part

Cryopreservation has become an essential tool in Assisted Reproductive Technologies and management of infertile couples. Embryo freezing in IVF is becoming more common, with a crescent percentage of children born from frozen embryos. The question of the possible impact of freezing/thawing processes on the offspring's health arises, especially as freezing techniques have evolved with the introduction of vitrification. While the available data are generally reassuring, even highlighting better perinatal outcomes for the risks of hypotrophy and prematurity, they also point out an over-risk of fetal macrosomia, for the moment poorly explained and which justifies to further evaluate long-term surveillance of children born after frozen embryo transfers.

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