Médecine de la Reproduction
MENUHealth of children born after frozen-thawed embryo transfer Volume 21, issue 4, Octobre-Novembre-Décembre 2019
Tables
- Key words: health of children, offspring's health, embryo cryopreservation, vitrification
- DOI : 10.1684/mte.2019.0767
- Page(s) : 308-12
- Published in: 2019
Cryopreservation has become an essential tool in Assisted Reproductive Technologies and management of infertile couples. Embryo freezing in IVF is becoming more common, with a crescent percentage of children born from frozen embryos. The question of the possible impact of freezing/thawing processes on the offspring's health arises, especially as freezing techniques have evolved with the introduction of vitrification. While the available data are generally reassuring, even highlighting better perinatal outcomes for the risks of hypotrophy and prematurity, they also point out an over-risk of fetal macrosomia, for the moment poorly explained and which justifies to further evaluate long-term surveillance of children born after frozen embryo transfers.
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