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Large vessel vasculitis : diagnosis and follow-up using non-invasive imaging technology


Sang Thrombose Vaisseaux. Volume 17, Number 4, 225-35, Avril 2005, Mini-revue

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Author(s) : Thomas Quéméneur, Eric Hachulla, Maryse Perez-Cousin, Jean-Paul Bérégi, Marc Steinling, Pierre Yves Hatron

Summary : Giant-cell arteritis and Takayasu’s arteritis are the two mainly large vessel arteritis. Conventional x-ray angiography was formerly used to screen for stenosis or vessel occlusion. Currently, echo-Doppler sonography, computed tomography and magnetic resonance imaging are emerging as fast and reliable methods to assess vessel anatomy and luminal status. Each method provides different information on stenosis, occlusion, dilatation and wall thickness and may be helpful in the diagnosis and estimation of disease activity. A dark halo of the temporal artery on echo-Doppler is highly suggestive of giant-cell arteritis. An aortic wall thickness on CT or MRI is highly suggestive of aortitis. 18FDG-PET seems to be a high sensitive and effective method for detecting disease activity particularly in Takayasu’s arteritis when biological inflammatory markers have failed but this needs to be confirmed in prospective studies.

Keywords : aortitis, giant cell arteritis, Takayasu’s arteritis, MRI, computed tomography, radionuclide imaging, echo-Doppler

 

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