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 Printable version |
Prophylactic antibiotics in vascular surgery |
Sang Thrombose Vaisseaux. Volume 13, Number 2, 113-8, Février 2001, Mini-revues
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 Résumé
Article gratuit
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Author(s) : Armand Bourriez, Christine Cheval, Claude Laurian |
Summary : The efficacy of prophylactic antibiotic therapy in surgery is a recent concept. In vascular surgery, it has decreased the frequency of prosthetic infections which often have dramatic consequences, and also the frequency of wound infection which increases the length and costs of hospitalisation. In 1978, Kaiser [1] demonstrated the benefits of prophylactic antibiotics in vascular reconstructive surgery: 585 patients were divided into two comparable groups. One group received a first generation cephalosporin, cefazolin, and the other group (Group II) was given a placebo. The study showed a significant reduction of wound infections (0.9% versus 6.8% in the placebo group) and a reduction in prosthetic infection (1 versus 4 in the placebo group). |
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