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 Printable version |
Hyperlipaemia and oral contraceptives |
Sang Thrombose Vaisseaux. Volume 11, Number 10, 761-5, Décembre 1999, Mini-revues
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 Résumé
Article gratuit
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Author(s) : Luc Foubert |
Summary : Oral contraceptives (OCs) influence lipoprotein metabolism; estrogens increase the HDL-cholesterol and triglycerides levels, and decrease LDL-cholesterol and Lp(a) levels; progesterones, depending on their androgenic potency, have opposite effects.
The cardiovascular risk associated with OCs is a thrombo-embolic and not an atherogenic risk. This risk is decreased with the use of low estrogen dose, and is increased with other factors, such as smoking, hypertension and hypertriglyceridaemia.
OCs with low estrogen dose can be used in moderate hypercholesterolaemia (below 300 mg/dl) for younger women (less than 35 years) without other risk factors. OCs with estrogen are contraindicated in women with hypertriglyceridaemia (> 200 mg/dl). |
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