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 Printable version |
Functional role of subthalamic nucleus in emotional processing: what can we learn from subthalamic nucleus deep brain stimulation in Parkinson's disease? |
Revue de neuropsychologie. Volume 3, Number 3, 181-8, Septembre 2011, Mini-revue
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 Résumé
Texte intégral
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Author(s) : Julie Péron |
Summary : Subthalamic nucleus deep-brain stimulation Parkinson's disease patient model seems to represent a unique opportunity for studying the functional role of the subthalamic nucleus in human emotional processing. There is growing evidence of a link between emotional impairments and deep-brain stimulation of the subthalamic nucleus, a treatment that constitutes a therapeutic advance for severely disabled Parkinson's disease patients. In this context, after a definition of emotional processing according to a multi-component view, the aim of the present review will consist in providing a synopsis of the studies that investigated the emotional disturbances observed in subthalamic nucleus deep brain stimulation Parkinson's disease patients. This review leads to the conclusion that several emotional components would be disrupted after subthalamic nucleus deep brain stimulation in Parkinson's disease: subjective feeling, neurophysiological activation, and motor expression. Finally, we will discuss the functional roles of the striato-thalamo-cortical circuits and the subthalamic nucleus in emotional processing. It seems reasonable to conclude that the striato-thalamo-cortical circuits are indeed involved in emotional processing and that the subthalamic nucleus plays a central in role the latter. |
Keywords : subthalamic nucleus, emotion, theory of mind, Parkinson's disease, deep brain stimulation |
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