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Henoch-Schönlein purpura


Médecine thérapeutique / Pédiatrie. Volume 14, Number 5-6, 349-54, Septembre-Décembre 2011, Dossier

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Author(s) : Brigitte Bader-Meunier

Summary : Henoch-Schönlein purpura (HSP) is an acute small-vessel leucocytoclastic vasculitis, which is the most common vasculitis in children. In most cases, HSP is a self-limited condition, which resolves spontaneously. Nephritis is the one feature of HSP that may have chronic consequences, and the long-term prognosis heavily depends on the severity of nephritis. Renal biopsy has to be promptly discussed in children who present with proteinuria greater than 0,5 g/L, renal insufficiency and/or nephrotic syndrome.

Keywords : leucocytoclastic vasculitis, purpura, immunoglobulin A, glomerulonephritis, corticosteroids

 

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