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Primary non Hodgkin's lymphoma of the uterine corpus. Case report and review of the literature


MT / médecine de la reproduction, gynécologie et endocrinologie. Volume 14, Number 1, 42-6, Janvier-Février-Mars 2012, Cas clinique

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Author(s) : S. Mahdaoui, S. Hermas, F. Ouadirga, M. Noun, N. Samouh, S. Benyad, S. Azouzi, S. Zamiati

Summary : The primary non Hodgkin's lymphoma of the uterus is rare, since only seven cases have previously been published. This rarity explains certain difficulty of the histological diagnosis and on the absence of a clearly established therapeutic strategy. We report a case of primary non Hodgkin's lymphoma of the uterine corpus \; diagnosed by endometrial biopsy during explorative laparotomy, in a 31-year-old patient suffering from uterine bleeding. Pathological analysis concluded the uterine mass to represent diffuse large B-cell lymphoma. Further staging had not revealed nodal or other extranodal localization [Ann Arbor stage IE] and there were no signs of recurrence during follow-up. Therefore the diagnostic criteria for true primary non Hodgkin's lymphoma of the uterine corpus were met. The patient was successfully treated by chemotherapy with CHOP. After 30 months of follow-up, she has no residual or recurrent disease.

Keywords : non-Hodgkin lymphoma, primitive, uterus, chemotherapy

 

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