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Spontaneous abortion and obesity |
MT / médecine de la reproduction, gynécologie et endocrinologie. Volume 13, Number 4, 257-64, Octobre-Décembre 2011, Mini-revue
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 Résumé
Texte intégral
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Author(s) : Céline Faure, Nathalie Sermondade, Achraf Benammar, Isabelle Cedrin-Durnerin, Rachel Levy |
Summary : Miscarriage concerns approximately 15% of pregnancies\; with a 1% recurrent fetal loss (RFL). The etiologic investigation is often disappointing. Nutritional factors represent a promising aspect, insufficiently investigated even if numerous studies underline their impact on fertility, gametogenesis, embryonic development and pregnancies outcome. Obesity is considered as an independent risk factor for miscarriage, involved in oocyte and embryo quality, but also in endometrial receptivity. The male part involved in miscarriage was for a long time under-estimated, neglecting the role of sperm in embryo development. If conventional sperm analysis remains essential, new investigations have to be considered such as sperm DNA or oxidant stress evaluation. It is particularly important to take into account overweight/obesity as favoring miscarriage because it represents a flexible factor on which intervention is possible to improve pregnancy outcome, with toxic eviction and recommendations for diversified and well-balanced food. |
Keywords : miscarriage, nutrition, obesity, overweight, sperm |
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