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 Printable version |
Post natal follow-up of antenatal multicystic renal dysplasia |
MT / médecine de la reproduction, gynécologie et endocrinologie. Volume 12, Number 2, 100-2, avril-mai-juin 2010, Congrès de médecine fœtale 2010, Morzine
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 Résumé
Texte intégral
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Author(s) : Georges Deschênes |
Summary : Unilateral multicystic dysplastic kidney is the most drastic anomaly of the metanephros development. The frequency of the disease has been estimated at 1/4,300 live births. The main concerns of this disease are the follow-up of the involution of the cystic structure and the development of a compensatory hypertrophy of the contralateral kidney, the risk of a contralateral urinary tract malformation and an ipsilateral genital malformation in male as well as in female, the risk of a nephron reduction with hypertension and the progression to chronic renal failure, the risk of an association to a mutation in the HNF1-β gene. The risk to develop a neoplasy in the cystic structure is likely to be similar to those of the general population. The post natal follow-up has to deal with these different issues and to select patients that will need long term follow-up at adult age. |
Keywords : HNFI-beta, renal cyst, chronic renal disease, hypertension, genital malformation, nephroprotection |
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