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Are pregnancy and ART reasonable after conservative treatment of a borderline or invasive ovarian cancer?


MT / médecine de la reproduction, gynécologie et endocrinologie. Volume 10, Number 4, 277-81, juillet-août 2008, Revue

Résumé   Article gratuit  

Author(s) : Jean-Marie Antoine

Summary : After conservative treatment of borderline or early invasive ovarian tumors, preservation of fertility and/or treatment of infertility are essential parts of quality of life in young women. When the oncological treatment does not allow keeping the ovaries, embryo, oocyte and/or ovary cryopreservation can be regarded as appropriate. For usual borderline tumors, including late stages without invasive implants, conservative surgery is usually possible. If it proves necessary secondarily, acceptable pregnancies rates can achieve by ART, with little or no increase in recurrences, which usually are of borderline type without any influence on overall survival. The problem is very different after invasive ovarian cancer: much lower frequency, later age of diagnosis, very restrictive indications of conservative surgery, increased risk of infertility by frequently associated chemotherapy. Very little data are available about the results and risks of ART in these circumstances. They encourage the utmost caution.

Keywords : borderline ovarian tumor, ovarian cancer, infertility, ovarian stimulation, ART, IVF

 

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