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Trauma and psychosis: a few neurobiological leads |
l'Information Psychiatrique. Volume 86, Number 6, 505-11, juin-juillet 2010, Neurosciences
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 Résumé
Texte intégral
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Author(s) : Jacques Thonney, Philippe Conus |
Summary : Numerous studies have documented a correlation between the occurrence of a traumatic experience during childhood or adolescence and the development of a psychotic disorder. Current neurobiological research highlights mechanisms that might explain this relationship by looking, on the one hand, at hypothalamic-pituitary-adrenal involvement in stress response, and on the other hand at the interaction between the polymorphism of certain genes and external stressors. However, there is no established causal link giving rise to different diathesis-stress models. |
Keywords : psychosis, schizophrenia, mental trauma, stress, aetiology, risk factors, neurobiology |
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