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Liver and celiac disease |
Hépato-Gastro. Volume 19, Number 2, 94-104, Février 2012, Mini-revue
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 Résumé
Texte intégral
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Author(s) : Cindy Neuzillet, Valérie Paradis, Dominique Valla |
Summary : Celiac disease (CD) is an autoimmune enteropathy caused by the ingestion of gluten, which is derived from wheat, barley and rye, in genetically predisposed individuals. This disorder is common (1/100 to 1/150 people) but its true prevalence is likely to be higher due to asymptomatic (silent or latent) forms. Although the small bowel is the main target of the disease, many extraintestinal manifestations have been described involving other organs, in 20 %-30 % of celiac patients. The association of CD with various forms of liver disease has been reported. Among them, celiac hepatitis, primary biliary cirrhosis and autoimmune hepatitis are the most frequent. The aim of this article is to review the spectrum of liver disorders related to CD and discuss their epidemiology, pathogenesis, diagnosis and treatment. |
Keywords : celiac disease, hypertransaminasemia, celiac hepatitis, primitive biliary cirrhosis, autoimmune hepatitis, MC, maladie cœliaque, IL, interleukine, TGt, transglutaminase tissulaire, CPA, cellule présentatrice d’antigène, RSG, régime sans gluten, N, fois limite supérieure de la normale, PBH, ponction biopsie hépatique, TH, transplantation hépatique, CBP, cirrhose biliaire primitive, HAI, hépatite auto-immune, RCH, rectocolite hémorragique, CAI, cholangite auto-immune, IFN, interféron, VHC, virus de l’hépatite C, VHB, virus de l’hépatite B, NAFLD,
nonalcoholic fatty liver disease, NASH,
nonalcoholic steatohepatitis, stéatohépatite non alcoolique |
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