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 Printable version |
Medically intractable seizures originating from the primary somatosensory hand area |
Epileptic Disorders. Volume 10, Number 4, 339-48, December 2008, Anatomo-electro-clinical correlations with video sequences
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 Résumé
 Free Article
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Author(s) : Mohamad Z Koubeissi, Robert J Maciunas, Adriana Tanner, Hans O Lüders |
Summary : [Case records of Epileptic Disorders. Anatomo-electro-clinical correlations. Case 03-2008] A 33-year-old woman had begun having intractable somatosensory seizures affecting the left hand since the age of 13 years. Occasionally, her seizures progressed to left arm posturing followed by secondary generalization. Scalp EEG revealed interictal epileptiform discharges in the right posterior quadrant, but with no ictal EEG correlates. Brain MRI showed a right temporal encephalomalacia, sparing mesial temporal structures, suggestive of a perinatal vascular insult. Ictal electrocorticogram, electrical stimulation mapping, and somatosensory evoked potentials localized the ictal onset to the hand area of the postcentral gyrus. Resection of that area resulted in total resolution of seizures with no significant lasting deficits. Potential complications of resecting the primary somatosensory hand area can be severe, as proprioceptive sensory loss may be permanent, resulting in significant disability. Such deficits may be temporary however, and the literature continues to report conflicting results regarding postsurgical outcome. Cortical plasticity may explain recovery of sensory deficits after partial resection of the primary somatosensory hand area. Multiple subpial transections of that area are sometimes performed to minimize functional deficits, but seizure control may be less optimal than with cortical resection. |
Keywords : somatosensory seizures, intractable epilepsy, cortical mapping, epilepsy surgery, cortical plasticity |
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